 |
|
| New assays available within last 6 months |
|
|
| in vitro pharmacology |
|
| ion channels |
 Membrane ligand-gated channels |
|
|
GABAA - antagonist automated patch-clamp |
3393 |
|
|
GABAA - potentiation automated patch-clamp |
3394 |
|
|
GABAA - antagonist conventional patch-clamp |
3395 |
|
|
|
3396 |
|
|
|
| Kinases |
| Protein-serine/threonine kinases |
|
|
MEK1/MAP2K1 |
3293 |
|
|
| Other kinases |
|
|
TBK1 |
3347 |
|
|
ULK1 |
3346 |
|
|
ULK2 |
3348 |
|
|
|
| ADME-Tox |
|
| in vitro drug absorption / drug transport |
| A-B Permeability |
|
|
A-B Permeability (Caco-2, pH 6.5/7.4) |
3318 |
|
|
A-B Permeability (Caco-2, pH 7.4/7.4) |
3319 |
|
|
| B-A Permeability |
|
|
B-A Permeability (Caco-2, pH 6.5/7.4) |
3320 |
|
|
B-A Permeability (Caco-2, pH 7.4/7.4) |
3321 |
|
|
| P-glycoprotein Interactions |
|
|
P-gp Inhibition (Caco-2, 3H-digoxin substrate) |
3349 |
|
|
|
|
| 2010 New standard profiles |
|
|
| In Vitro Pharmacology |
| PDE High Throughput Profile |
|
