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In vitro pharmacology 2010 catalog
Over 960 assays, among which 98 are new assays and 57 assays follow a new protocol:
 210 non-peptide & peptide receptors including 143 GPCRs
17 nuclear receptors
320 cellular assays, including both agonist & antagonists
effects for 129 functional GPCR targets, and both stimulant
and inhibitor effects for16 kinase assays
396 enzymes, including 270 kinase assays
54 tissue assays
41 ion channels
9 transporters
Sub-cellular, cellular and tissue preparation
More than 80 % are human targets
Close to 100 assays (e.g. Specialized cellular assays, animal
models...) are now available as part of our custom research.
For further information, please contact us:
customresearch@cerep.com
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ADME-Tox 2010 catalog
Over 175 assays, among which 22 are new assays in order to assess:
Bioavailability in vitro and in vivo with evaluation of:
Physicochemical properties
Drug absorption & Drug metabolism
In vivo PK & in vivo BBB
Drug-drug interactions:
CYP-mediated (inhibition and induction)
P-gp mediated (inhibition)
In vitro toxicity:
Cytotoxicity
Neurotoxicity
Cardiac toxicity
Genetic toxicity
Many assays are suitable for evaluating the ADME-Tox properties of compounds early in the
drug discovery process while others are designed with the intent to meet regulatory
requirements making them suitable for later stage development.
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 Assay catalog references
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In 2009, Cerep finalized one of the milestones in the industrialization process: the implementation of new referencing and supply chain management
systems. The references of each of the assays have thus been simplified: each reference will now be displayed as 4 digits.
A cross-reference table between old and new assay references is available here
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Prices
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As most of our clients have witnessed over the past few years, Cerep’s pricing strategy has been to forthcomingly share economy of
scale whenever the volume of data to be generated allowed it. In this context, and in view of sustainable development, Cerep has
decided to start decreasing catalog printing volume and in 2010 stop publishing 3 catalogs for the different currencies. Prices
will be made available in separate price list. Please inquire
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Ordering a catalog (hard copy)
